Ointment bases examples. Properties: Greasy and occlusive.

Ointment bases examples 3–5. Relate the composition and type of ointment base to the release of a drug contained therein. Oleaginous bases . Eur. Extemporaneously prepare each type of ointment base and incorporate a solid drug into it. Diadermic ointments – The drugs present in these types of ointments enter Apr 15, 2018 · Ointment - Download as a PDF or view online for free. Design. Rate spreadability as easy or difficult. There are 4 main ointment bases: A medical professional administering nose drops Instillation of eye drops. Examples of water-absorbing bases include organic The ointment is applied as a narrow band of approximately 0. Humectant emollients contain ingredients such as urea, glycerol, propylene glycol or lactic acid that attract and hold water in the top layer of skin. Emulsion Ointment Base (O/W): 1. Petrolatum USP is a purified hydrocarbon mixture from petroleum; Examples include Vaseline Feb 16, 2021 · Examples of ready-to-use preparations: Ash Base Fatty Ointment, Dermatop Base Fatty Ointment, Excipial Almond Oil Ointment, Neribas Fatty Ointment, Kerasal Base Ointment, Topisolon Base Fatty Ointment. Hydrocarbon Bases—Hydrocarbon bases, known also as ‘‘oleaginous ointment bases,’’ are f) These bases act as occlusive dressing. Uses: Provides prolonged action, prevents moisture loss. Sep 15, 2015 · Hence selection of ointment base is very important aspect of their formulation. Example: Benzocaine ointment. Examples of oleaginous bases include white petrolatum, mineral oil Aug 15, 2020 · • There are three official anhydrous Water miscible ointment base. Water-absorbing bases are greasy but allow absorption of water. Subjects. Epidermic bases (little or no skin penetration) Endodermic bases (moderate skin penetration) Diadermic bases (high skin penetration) Examples of Ointment Bases. Ointment base with Example:- Type of Ointment bases (according to USP) May 13, 2020 · These bases are premixed and readily available for the pharmacist, into which the API is generally incorporated with the help of an ointment spatula or triturated using a mortar and pestle. At the end of the semester, students completed a dry laboratory 1. Each therapeutic ointment possesses as its base one of these four general classes. By melting the ingredient into the base, the soluble constituents are dissolved. These ointments contain medicines in the form of fine particles. When it is necessary to add an aqueous preparation to a hydrophobic base, the solution first may be incorporated into a minimum amount of a hydrophilic base and then •Must put into consideration the ointment base’s capacity to accept the volume required. (iii) Wool alcohols ointment B. It is common to use a levigating agent, such as glycerin and liquid petrolatum, to improve wetting of powders for incorporation into ointment bases. Composition: Made from hydrocarbons like petrolatum or paraffin. In this video we had discussed about Formulation of Ointments and Ointment Bases. Rate washability as washable or non-washable. The major component in a typical ointment is petrolatum (also called petroleum jelly, white 6 days ago · Here’s an explanation of the key roles of excipients in ointment, cream, and gel formulations: 1. Examples: White petrolatum, Vaseline®. It describes ideal properties for ointment bases and classifies common types, including oleaginous, absorption, emulsion, and water soluble bases. false and more. Design. Nov 6, 2019 · Aqueous solutions can be incorporated into these bases. W/O absorption ointments. Hydrocarbon (Oleaginous) Bases. depends upon purpose for which ointnent is going to be applied. Study with Quizlet and memorize flashcards containing terms like Ointment, Hydrocarbon bases Absorption bases Water removable bases Water soluble bases, Ointment base and more. (v) Macrogol ointment B. Test your knowledge on the properties and uses of these bases in formulation science. The non-emulsified bases absorb water and aqueous solution producing w/o emulsion e. Ideal bases contain the following characteristics-It must be Inert, non-irritating, and non-sensitizing in nature. Unlike hydrocarbon and absorption bases, a large proportion of aqueous phase can be incorporated into water-removable bases with the aid of suitable emulsifying agents. polymer which exists in liquid, semisolid The ointment base needs to be heated to above its melting temperature prior to the addition of the other ingredients. The USP defines these bases as creams. Types of Ointments Bases. Study with Quizlet and memorize flashcards containing terms like types of ointment bases, characteristics of oleaginous bases, characteristics of petrolatum and more. The main drawback of ointments without emulsion base is their greasy and sticky nature. Ointment is applied on hands, legs, face, eyes, ears, vagina, anus, throat etc. The ointment base is prepared and the This quiz covers the various types of ointment bases used in pharmaceutical applications. Fusion Types of ointment bases. Name Ointment Bases Accession Number DBCAT002024 Description. 3 days ago · Ointments are preparations for external application but differ from creams in that they have greasy bases. The oily phase forms an occlusive covering which prevents loss of water by evaporation. Oil-in-water emulsions easily washed off skin; Can absorb serious discharges; Water Soluble Base. true B. Type of preparation: Absorption base. Examples of Water-Soluble Bases • For medicated ointments and ointment bases containing waxes which are solid at room temp and not easy to triturate Mar 19, 2012 · Water-soluble bases • PEG ointment, NF - PEG 3350 400 g, PEG 400 600 g - Polyethylene glycol 200, 300, 400 (4-8oC), 600 (20- 25oC), 1000, 1450, 3350, 4000, 6000, 8000 and 20000 - Only a small amount of liquid (<5%) can be incorporated - If 6-25% of liquid is to be incorporated, 50 g of the 400 g of PEG 3350 may be replaced with stearyl Sep 28, 2020 · 2. Jun 29, 2023 · Types of Ointment, Ointments are classified as: Epidermic ointment, Endodermic ointment, Diadermic ointment and Antibiotic ointment,. The base is usually anhydrous and immiscible with skin secretions. Study with Quizlet and memorise flashcards containing terms like Are oleaginous bases hydrous or anhydrous?, Are oleaginous bases hydrophobic or hydrophilic?, Are oleaginous bases spreadable? and others. Different bases are chosen based on the intended application and patient preferences. •Must put into consideration the ointment base’s capacity to accept the volume required. Jan 23, 2014 · W/O emulsion bases. Oleaginous bases are water repellent and include representatives of animal, vegetable, and mineral origin. A flowchart was designed to help students select the appropriate base for an ointment. Students used • Yellow ointment • All are examples of hydrocarbon ointment bases. Effect of the drug on the consistency of the ointment base. Incorporation of Liquids via Absorption bases. ) W/O creams. Various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons; vehicles for medicinal substances intended for external application; there are four classes: hydrocarbon base, absorption base, water-removable base and water-soluble base; several are also emollients. 20. 4-Stability of the drug in the ointment base . Ointments B. However, gels have different physical characteristics - poly base example = PEG ointment, Mupirocin 2% ointment, Lidocaine 5% ointment Incorporation of medication to a performed emulsion: Evaluation of Ointment Bases. The choice of ointment base depends upon the nature of medicament, stability of ointment and clinical indication of the Ointment. Absorption base component Emollient and plasticizer in ointments As outlined when discussing absorption bases, the drug may also be dissolved in water to form a solution to be levigated into an ointment base or cream. To improve students’ skills in selecting appropriate ointment bases through the development and implementation of a flowchart. Creams C. Bases are the primary and significant ingredient in any semi-solid dosage form. Formula: Macrogol 4000. 25 g Propyl paraben 0. base. Vaseline, white Ph. 1. Excipients are used to create the base or vehicle of the topical formulation, providing the desired consistency and texture. Non-water washable. Endodermic ointments – The drugs present in the these types of ointments exert their action on the deeper layers of cutaneous tissue. Water-soluble bases are comprised of only water-soluble components and no oleaginous compounds. Jun 23, 2016 · The choice of ointment base depends upon the nature of medicament, stability of ointment and clinical indication of the ointment. They are ideal for drugs that are not water-soluble and need prolonged contact with the skin for absorption. Examples—Lanolin, Rose water Ointment, Cold Cream B. Hydrocarbon bases are widely used in Dec 20, 2023 · Example: Sulfacetamide sodium ointment. Study tools. Gels, Protectants, lubricants, emollients, drying agents, astringents A. As stated previously, the USP recognizes four general classes of ointment bases to be used therapeutically or as vehicles for active ingredients . So, chose the suitable ointment base which should keep phenol in solution form. false, 4 ointment bases, Oleaginous bases are easy to wash off due to their miscibility with water A. Oct 7, 2015 · There are three major types of ointment bases: oleaginous (greasy) bases, water-absorbing bases, and water-miscible bases. Fusion method In the fusion technique, drugs and other solids are dissolved in an ointment base and then combined. Oleaginous Bases B. A topical medication is a medication that is applied to a particular place on or in the body. Cetomacrogel Emulsifying ointment B. Set aside at least 55 g to use next week in Step 4 below. 3 Aug 12, 2024 · 2% for pourable emulsions, 10% for stiffer emulsions such as aqueous cream BP, 3–30% may also be mixed with soft and liquid paraffin to prepare anhydrous ointment bases, for example, emulsifying ointment BP. Nov 19, 2021 · Water–Removable (Water-Washable) Bases or emulsion base (O/W emulsion bases) most commonly used type of ointment base (creams are 0/w emulsion) Emulsion bases are washable and are removed easily from skin or clothing. For example, Hydrocortisone Ointment, Bacitracin Ointment, and Lidocaine Ointment. The bases used are combinations of PEG 300 and PEG 3350, cetyl alcohol and cetyl esters, wax, liquid paraffin and white paraffin. 2. Pack in a 2 oz. Properties: Greasy and occlusive. • Example :- Emulsifying ointment B. Petrolatum, USP: Petrolatum, USP is a purified mixture of semisolid hydrocarbons obtained from -partition of water-insoluble drug into the skin may decrease in an oleaginous phase due to the drug's affinity toward the formulation-lipophilic drug release can be significantly increased when the ointment base shows an increased water affinity-water-soluble and water-removable bases would be the choice for rapid release of lipophilic drugs-the water-soluble base is also useful for drugs Study with Quizlet and memorize flashcards containing terms like Define an ointment, True or false, ointments can have systemic effects, True or false, topical preparations are used solely for local effects and more. C. Hydrophilic ointment USP is an example of a water-removable ointment base. B. 2 Absorption basesThe absorption bases are of two types: i) Non- emuJsified bases ii) Water in oil emulsion bases. It describes their composition, water content, affinity for water, spreadability, washability, stability, drug incorporation and release potential, occlusiveness, common uses, and examples of each type. Mar 28, 2024 · Water-soluble bases, also known as greaseless ointment bases, The choice of an ointment base depends on the desired action, the characteristics of the incorporated drug substance, and bioavailability. Water-based wool wax alcohol ointment DAB 2003 Jun 1, 2016 · (3) General Rule: Assuming that there are no compatibility problems with other ingredients in the formulation, levigating agents are usually chosen to be chemically similar to the ointment base. Create Study with Quizlet and memorize flashcards containing terms like Petrolatum, White Petrolatum, White Ointment and more. desirability of surface to which it is to be applied. Ointments usually contain a medicament or a mixture of medicaments dissolved or dispersed in the base. [4] OINTMENT BASES WITH EXAMPLE Type of Ointment bases (according to USP) Mainly ointment bases are of following types: 1) Oleaginous ointment base or hydrocarbon ointment base Oct 29, 2020 · Ointment base. Must consider ointment base capacity to accept liquids Phenol, for example, possesses no antiseptic action when incorporated in the fatty type of ointment base. synthetic esters, ABSORPTION BASES and more. HYDROCARBONS: -Petrolatum USP, White petrolatum -Yellow wax, white wax -Yellow ointment USP, White Ointment USP B. The desire for a base that is easily removed by washing with water. desirability of topical . 0 d0 30 What are 4 examples of ointment bases? 1) oleaginous bases 2) absorption bases 3) water removable bases, water washable bases 4) water soluble bases. B and What are some examples, Absorption Typer: Anhydrous Does it absorb water Examples, Absorption Type: Water in Oil Emulsion Ointment or Cream Can it absorb water Examples and more. Ointments 13 Classification of Ointment Bases: 1. • When powdered substances are to be incorporated into hydrocarbon bases, liquid petrolatum (mineral oil) may be used as the levigating agent. What are 5 examples?, What is an emulsifier?, What are the 3 main properties of ointments? and more. 3-Desirability of occlusion of moisture from skin . The confusing array of official (U. Ointment base can be referred to as the drug carrier part. absorption. Bases. There are four general classes of ointments: Hydrocarbon bases (oleaginous ointment bases) which keep medications in contact with the skin and can act as a moisturizer Describe the physical properties of ointment bases and determine the purposes for which they are best suited. Take about 5 g of each ointment and note the appearance. 00. For example, vanishing cream possess undermentioned ingredients forming oil in water type of emulsion Stearic acid 20 parts Pot. Base Selection and Consistency. Translations in context of "ointment bases" in English-Russian from Reverso Context: Or components pharmaceutically acceptable carrier, such as ointment bases, can be entered directly in the colloidal solution of nanoparticles. :- anionic emulsifier, ceterimide Emulsifying ointment B. Students used the flowchart throughout the semester in both dry and wet laboratory activities. Dec 13, 2015 · Ointments-Bases Appropriate Selection of Ointment Base: Selection of ointment base depends on the following : 1-Desired release rate of the drug substance from the ointment base . Greaseless bases that soften with water; Used for solid substance incorporation; Classification of Ointment Base Oleaginous Bases. Type of preparation: Water-soluble ointment base. The results of incorporating pilocarpine (V) (a relatively water-soluble dmg) and fluoro-metholone (a lipophilic dmg) into a water-inoil ointment base can be compared in Fig. • RECTAL OINTMENTS These are the ointments to be applied to the peri- anal or within the anal canal. 7. They may be either dissolved, dispersed or emulsified in an ointment base. There are four types of ointment bases: hydrocarbon bases (oleaginous ointment bases), absorption bases (water-in-oil emulsion), water-removable bases (cream), and water-soluble bases (gel) . Hydrophobic base gel DAB. Brownish discoloration indicates oxidation and loss of activity. Dec 13, 2018 · 2. Oleaginous bases are hydrophobic and primarily composed of greasy or oily substances. 5 5. The document discusses ointment bases, which are substances that act as carriers for medicaments in ointments. Dec 1, 2014 · CLASSIFICATION OF OINTMENT/ OINTMENT BASES • EMULSION BASES: A. Water Soluble Bases F. Liquid Study with Quizlet and memorize flashcards containing terms like White ointment (bleached/purified honeycomb), White petrolatum, Petrolatum (yellow) and more. Ointment Bases. - hydrophilic anhydrous materials (that can absorb water to form w/o emulsions) or - bases that are w/o emulsions and have the ability to absorb more water - emollient and occlusive (to a somewhat lesser degree than hydrocarbon bases) - greasy and difficult to remove (water immisible) - allow for incorporation of a limited amount of additional aqueous phase (for example a drug solution) Jun 1, 2016 · The choice of a particular base matches these factors with the properties of an ointment base class. Each therapeutic ointment possesses as its base a representative of one of these four general classes. Some of the semisolid bases that are commonly used in compounding pain creams include premium lecithin organogel (PLO), oleaginous base, Vanicream base (a) The most suitable Carbowax ointment bases are formulations of heavy and light molecular-weight polyethylene glycols, such as the formula below for Polyethylene Glycol Ointment, USP: Chemically and physically stable non reactive with variety of bases Free from objectionable odor Nontoxic or nonirritating Easy to apply and non greasy Remind in May 18, 2022 · Several limitations of ointment bases has been encountered timely as agglomeration, oil phase ingredients can form lumps, poor dispersion, poor drug delivery efficiency, make stained, immiscible Study with Quizlet and memorize flashcards containing terms like Which of the following topical dosage forms should be applied to dry and scaly lesions on the skin?, Give two examples of absorption ointment bases, Give two examples of ointment bases that cannot be used to prepare ointments by incorporation technique and more. Phenol, however, is used in dermatology less for its antiseptic properties than as an antipruritic, and the base used in the official ointment of phenol consists of a mixture of white beeswax, lard, hard paraffin, and soft paraffin. Describe the appearance and consistency (texture) of each ointment base. With the oleaginous base prepare preparation Those that permit incorporation of aqueous solutions or absorb water resulting in formation of w/o emulsions Example: Hydrophilic ointment Absorption Base Type 2 Those that are w/o emulsions (emulsion bases) that permit incorporation of additional quantities of aqueous solutions Study with Quizlet and memorize flashcards containing terms like OLEAGINOUS BASE OR HYDROCARBON BASE, A. Lanolin and cold cream are examples of ointments without emulsion bases. Not washable 5. In preparing ointment by spatulation, the pharmacist works the ointment with a stainless steel spatula but if the components react with metal (such as iodine, tannins, mercuric salts) the hard rubber is used. Absorption Bases. Wool fat, wool alcohol, bees wax and cholesterol. 15 g Sodium lauryl sulfate 10 g Propylene glycol 120 g Stearyl alcohol 250 g White petrolatum 250 g Purified water 370 g Study with Quizlet and memorize flashcards containing terms like oleaginous ointment base examples, absorption ointment base examples, water/oil emulsion base examples and more. Absorption Bases3. The shearing force must be considered to avoid grittiness. Ingredients are mixed until uniform mixture is attained via Mortar and Pestle, Spatula and Porcelain Tile, or Ointment Mill 2. Ointments are semi-solid topical pharmaceutical formulations that consist of a greasy or oily base. An ideal ointment base should be inert, stable, smooth, compatible with the skin, non-irritating and should release the incorporated medicaments readily. The key components of an ointment formulation are carefully selected to ensure the desired consistency, stability, and therapeutic effect of the final product. Examples of oleaginous bases include vaseline. American Journal of Pharmaceutical Education 2014; 78 (1) Article 16. In general, ointment bases may be classified into four general groups hydrocarbon, absorption, water-removable, and water-soluble bases. Ointment bases recognized for use as vehicles fall into four general classes: hydrocarbon bases, absorption bases, water-removable bases, and water-soluble bases. Emulsion (w/o) D. 5 Oil 50 40. Concentrations most often used are 20 mg/100 g ointment base (20 mg% concentration) or 40 mg/100 g ointment base (40 mg% concentration). Absorption Bases C. Classification of Ointment Bases - Compounding and Manufacturing: Water-Soluble Bases - Compounding and Manufacturing Examples. 5 inch. The invention also discloses application method of the oleaginous base in hot melt formulated, control substrate temperature be 40 DEG C~50 DEG C when add active ingredient be conducive to product mix uniform. Water Soluble Bases D and E These 2 posesses Water Washable characteristic ointment base: A. ointment jar. Ointment Bases Melgardt de Villiers, PhD ointment more specifically to indicate that a drug is incorporated into an oleaginous ointment base;for example,the name Hydrocortisone Ointment means The ointment base needs to be heated to above its melting temperature prior to the addition of the other ingredients. • Compound benzoic acid ointment used as anti fungal Common bases for ointments include: Petroleum jelly ; Anhydrous lanolin; Waxes; Vegetable oils; Lard; Ointments may also contain preservatives and fragrance. Incorporation 2. Emulsion (o/w) E. Hydrous 2. Example: Betamethasone ointment, Gentamicin ointment. 1 Vehicle (Ointment Bases) Ointment bases that act as carriers for the drug in formulation also control the absorption and drug delivery characteristics of the drug. Ointment Base Selection Flowchart. BASES PROPERTIES EXAMPLE Oleagenious bases Occlusive , hydrophobic, greasy, non-washable White petroleum, white ointment Absorption bases Occlusive , water absorbent, anhydrous, greasy Anhydrous lanolin, hydrophilic petroleum w/o type emulsion bases Occlusive , hydrous, greasy, hydrophilic , non- washable Lanolin, cold cream o/w type Objectives. Dec 7, 2024 · Types of Ointment Bases. RECTAL OINTMENTS These are the ointments to be applied to the peri- anal or within the anal canal. Mixing speeds and shear can be increased when the ointment base is liquid, to uniformly disperse the functional ingredients. For scientific understanding of percutaneous absorption of ointment bases it is essential to get familiar with skin structure in relation to drug absorption [14]. Examples: Ketoconazole ointments. cream base and white petrolatum were collapsed together and compared to the number of students who selected the correct base (an anhydrous, hydrophilic absorption base such as Aquaphor) using chi-square analysis. Selection of the Appropriate Base • Selection of the base to use in the formulation of an ointment depends on careful assessment of a number of factors, including the following: • Desired release rate of the drug substance from the ointment base • Desirability of topical or percutaneous drug absorption • Stability of the drug in the ointment base • Effect, if any, of the drug on Jul 31, 2024 · Table 4 details the level of skin penetration of varying ointment bases, and Table 5 provides the polarity and spreadability of common lipid components of ointment bases. Low-shear or mixing speeds are typically used when the ointment base or finished formulation is cold/thick. Hydrocarbon gels. Examples: Demodex ointment. Oleaginous ointment bases Apr 16, 2024 · A molten liquid base, a liquid base, or a semisolid base is used to rub coarse powder. -hydrophobic Study with Quizlet and memorize flashcards containing terms like Petrolatum, White petrolatum, yellow ointment and more. 1,4. 3. RECTAL OINTMENTS These are the ointments to be applied to the peri-anal or within the anal canal. ANIMAL FAT/VEGETABLE OILS C. Will absorb water 3. OINTMENT BASES24,25,26,27 The vehicle or carrier of an ointment is known as ointment base. Semi Solid DFs, Routes of Administration, ointment, paste, cream, ideal properties of a base, characteristics of ointment bases & specific examples, general preparation methods of ointments Hydrophilic ointment USP is an example of a water-removable ointment base. Composition: Hydrocarbon bases with the ability There are 4 main ointment bases: Vegetable oils like as coconut oil, sesame oil, olive oil, almond oil and peanut oil. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. Cholesterol: 0. 6. Aug 30, 2023 · The oleaginous ointment base is a mixture of liq- Polyethylene glycol ointment, is an example of. They are also known as “greaseless ointment bases” by the USP. Stability of the drug in the ointment base. 05. The present invention relates to the ointment oleaginous base containing vaseline, liquid paraffin, the matrix also contains Compritol 888 ATO. Each has very specific and unique characteristics (5, 6). 25 - 0. P. Oleaginous bases (Hydrocarbon) Absorption bases Water-removable bases Water-soluble bases Oleaginous Bases When applied to the skin they have an emollient effect, protect against the escape of moisture, are effective as occlusive dressings and remain on the skin for long periods without drying due to their immiscibility with water. 2. Insoluble in water 4. It is easy to remove these bases from the skin due to their hydrophilic nature. Ointment Bases: The ointment base is that substance or part of an ointment preparation which serves as carrier or vehicle for the medicament. 3. . Various types of ointment bases may be employed for ocular administration, as follows. Wool Wax Alcohol Ointment DAB 2003. - If phenol used in solid form with ointment bases it causes blisters. The ointment base is placed on one side of the working surface. Solvent properties: - Most of the medicaments incorporated with ointment bases are insoluble with it so, necessary to mix finely powdered drug in ointment bases. They are used as emollients. Scheduled maintenance: October 2, 2024 from 07:00 PM to 08:00 PM May 11, 2023 · As is the case for all ointment formulations, ophthalmic ointments are prepared by dispersion of the therapeutic agent in the pre-prepared ointment base. Water-Oil-Emulsion 6. It provides examples of ingredients commonly added to ointment bases like preservatives, humectants, antioxidants, and chelating agents Selection of The Appropriate Base • Selection of the base to use in the formulation of an ointment depends on careful assessment of a number of factors, including the following: * Desired release rate of the drug from the ointment base * Desirability of topical or percutaneous drug absorption * Desirability of occlusion of moisture from the skin 1. Herbal drugs are also formulated in the form of ointment. What is Cream? Mar 16, 2018 · For example, only very small amounts of an aqueous solution may be incorporated into an oleaginous ointment, whereas hydrophilic ointment bases readily accept aqueous solutions. Characteristics of the skin surface to which it is applied. must know Petrolatum, white petrolatum, white ointment and yellow ointment are examples of hydrocarbon ointment bases. Emulsion Ointment Base (W/O): 1. Table 4 Ointment Base by Skin Penetration The use of mechanical shear or a combination of fusion processes and mixing can be used to facilitate the dispersion or dissolution of the ingredients in the base to form a single-phase ointment . Examples: white petrolatum, yellow ointment, white ointment. Type of preparation: Water-miscible ointment base. Oct 11, 2024 · Study with Quizlet and memorize flashcards containing terms like Oleaginous bases, Thus, oleaginous bases have the following properties:, Oleaginous ointment bases show the following properties when applied to the skin: and more. For example, mineral oil is the levigating agent of choice for oleaginous bases, such as hydrocarbon, absorption, and water-in-oil emulsion bases (see Jun 1, 2016 · (3) General Rule: Assuming that there are no compatibility problems with other ingredients in the formulation, levigating agents are usually chosen to be chemically similar to the ointment base. When powdered substances are to be incorporated into hydrocarbon bases, liquid petrolatum (mineral oil) may be used as levigating agent. –Oleaginous base (white petrolatum) – little amount of water –Hydrophilic Bases (PEG or Polyethylene Glycolor Macrogol) – Readily accept aqueous solutions •Absorption base, Emulsion Base, Water soluble base are HYDROPHILIC BASES 3 days ago · Here are the different types of ointment bases commonly used: 1. The 20 mg% strength is usually used The selection of an ointment base in which drugs are to be incorporated for local application should depend on the condition of the patient's skin, the biological effect desired, and the pharmaceutical compatibility of the ingredients with each other and the base. Jan 1, 2009 · base; for example, the name Hydr ocortisone Ointment means that hydrocortisone is incorpo- Simple ointment bases were prepared using hard paraffin, cetostearyl alcohol, white soft paraffin and The ointment base needs to be heated to above its melting temperature prior to the addition of the other ingredients. The aqueous phase hydrates the skin. 5 Hydrocarbon/Oleaginous Base (Properties) Click the card to flip 👆 selection of appropriate base. Type of preparation: Hydrocarbon ointment base. 2-Rate and extent of topical or percutaneous drug absorption . Water-removable bases are O/W emulsions that can be easily washed off skin with water. Study with Quizlet and memorize flashcards containing terms like Hydrocarbon Base will it absorb water? The ointment base of Example 13 can be used for preparing the following medicinal products: Oint- Medicamem 532 523 w i ig m gd- Base, Water, ment icament ieament per cent per cent added 10 Oil 5O i0 Aqueous 60 40 0. Study with Quizlet and memorize flashcards containing terms like oleaginous ointment bases, oleaginous ointment bases examples, Absorption Ointment Bases and more. Ointment bases for ocular administration. Emulsion Bases4. Ointment bases not only act as the carriers of the medicaments but also control the extent of absorption of medicaments commixed in them. Water Soluble Bases 4) The ointment should be smooth and free from grittiness. An ointment is an unctuous semisolid for topical application. The Quality of the medicine, the stability and the area of the application can be determined by the ointment base . Non-ionic type. Oleaginous Bases (Hydrocarbon Bases) • have an emollient effect • protect against the escape of moisture • are effective as occlusive dressings • can remain on the skin for long periods without drying out • difficult to wash off Examples: Petrolatum, white petrolatum, white ointment, and yellow ointment 6 days ago · Ointment Formulation: Key Components. Water Soluble Base This document summarizes the key properties of different types of ointment bases, including oleaginous, absorption, water in oil emulsion, oil in water emulsion, and water miscible bases. These key components include: Ointment Base Increases the hydration of the stratum corneum; inhibits water loss from skin = increased penetration for some compounds Study with Quizlet and memorize flashcards containing terms like oleaginous base example, oleaginous base type, oleaginous base affinity for water and more. Fats and fixed oils such as lard Apr 26, 2024 · Water Removable Base. Study with Quizlet and memorize flashcards containing terms like What are the two types of ointments?, Preparations applied to the skin either for their physical effects or for the specific effect of a medicinal agent (SATA) A. sorbitansesquioleati. [1] Oleaginous Bases Click the card to flip 👆 Of all the Ointment bases this is the only one that Can't absorb water A. Oleoginous Bases2. Examples are Petrolatum, USP; White Petrolatum, USP; White Ointment, USP Oleaginous bases Two types: (1) Permit the incorporation of aqueous components resulting in Water-in-oil emulsions, and (2) water-in-oil emulsions that permit the incorporation of additional aqueous components. - Non- ionic emulsifier. These are semisolid or cream like consistency Both o/w and w/o type of bases are used in formulating emulsion bases processing a same physical characteristics like ointment. Example: Sulfacetamide sodium ointment. 8. Oleaginous Bases. Examples. Preparation of ointments Ointments are prepared by two general methods: 1. For example, mineral oil is the levigating agent of choice for oleaginous bases, such as hydrocarbon, absorption, and water-in-oil emulsion bases (see Hydrophilic ointment USP, is an example of this type of base. (iv) Emulsifying ointment B. ABSORPTION BASES • In the absorption bases contains small amount of water & they provide relatively less emollient properties than hydrocarbon bases. Study with Quizlet and memorize flashcards containing terms like Examples of hydrocarbon (oleaginous), Compatible levigating agent for hydrocarbon (oleaginous), Examples of anhydrous absorption and more. Figure 1. desrability of occlusion of moisture from skin. Study with Quizlet and memorize flashcards containing terms like Ointments are used for __________ application and treat a variety of topical disorders. • It is used for O/W creams. 0 do 5O 20. 0% w/w for topical pharmaceutical formulations. Example: Hydrophilic petrolatum Lanolin The ointment is applied as a narrow band of approximately 0. Hydrocarbon bases. Gels and more. • These bases are generally anhydrous substances which have the property of absorbing considerable quantity of water but still retaining their ointment like consistency. Skin penetration: oleaginous bases (none), absorption bases (moderate), water-soluble bases (high) Classification of Ointment Bases. –Oleaginous base (white petrolatum) – little amount of water –Hydrophilic Bases (PEG or Polyethylene Glycolor Macrogol) – Readily accept aqueous solutions •Absorption base, Emulsion Base, Water soluble base are HYDROPHILIC BASES Ointment bases recognized for use as vehicles fall into four general classes: the hydrocarbon bases, the absorption bases, the water-removable bases, and the water-soluble bases. 4. Therefore, the choice of an appropriate ointment base is determined on one or more of the following factors: Characteristics of the site of application (dry vs moist). The medicated stuff or the ingredients present inside the ointment is actually the main base of ointments. 3 days ago · Here are the different types of ointment bases commonly used: 1. 1. There are mainly three classes of ointments and they are differentiated based on the physical composition. Feb 12, 2014 · Objectives. Polyethylene glycol (PEG) is a. Aug 6, 2024 · Neobase, Vanishing Cream, and Hydrophilic Ointment is an example of: A. Epidermic ointments – The drugs present in these type of ointments exert their action on the epidermis of the skin. 1,4 Table 6 describes the five types of ointment bases with regard to varying characteristics, such as water washability. Velvachol is an example of which of the following types of ointment base? Water/oil emulsion Oil/water emulsion Absorption Oleaginous. Vaseline, yellow Ph. g. 5. Jul 8, 2023 · These are: 1. Occlusive emollients such as lanolin, emulsifying ointment, and liquid paraffin work by covering the skin with a protective film, preventing water loss. Emulsifying eye ointment (NRF 15. Cetomacrogol 1000 Study with Quizlet and memorize flashcards containing terms like which of the following ointment bases is an example of a water removable base? Hydrophilic ointment usp lanolin usp hydrophilic petrolatum usp white petrolatum usp, All of the following are properties of oleaginous bases except: Protect against the escape of moisture from the skin easily removable with only water provide an Dec 14, 2023 · EMULSION BASES. Ungt. Learn about hydrocarbon bases, absorption bases, water-removable bases, and water-soluble bases, along with their characteristics and classification. Study with Quizlet and memorize flashcards containing terms like Topical applications can be used for local but not systemic effects A. water-soluble base. Hydrophilic ointment, USP: Hydrophilic ointment has the following formula for the preparation of about 1000 g: Methyl paraben 0. Dec 12, 2019 · Examples of Oleaginous bases Petrolatum: - a purified mixture of semisolid hydrocarbons obtained from petroleum - color varies from yellowish to light amber - may be used alone or in combination of with other agents as an ointment base - also known as yellow petroleum and petroleum jelly - a commercial product is Vaseline May 6, 2022 · 10. In another method we can discuss different types of ointments on the basis of their action on different layers of skin. Hydrocarbon bases: hard paraffin, soft paraffin May 20, 2021 · (ii) Paraffin ointment base. White Petrolatum, White Ointment. Incorporation of solids into base via Comminution & Levigation, Geometric dilution 3. :- cationic emulsifier. Emulsion bases can be diluted with water; Cream like consistency; Prepared from emulsifying wax, white soft paraffin & liquid The ointment containing BCNU is prepared by mixing an alcoholic solution of BCNU with white petrolatum USP. stability of drug in ointment . • They have 2 An ointment has medicated ingredients which serve a protective, therapeutic, or prophylactic purpose when applied on the skin or mucous membranes . 2) Absorption ointment bases These bases categorize into two groups: A) Permit the incorporation of aqueous solution with the formation of water in oil type of bases. There are various parts of the body surfaces, skin and mucous membranes where ointment is applied for curing certain skin or disease conditions. Oct 9, 2021 · 9. 9. desired release of drug substance from ointment . itm tkxmj tkp mksnalr kjf stmv wmtoh xsus cex dltg